Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 6/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27846457 | 1.00 | LMNA (0.44) | LMNACTSKCTSSPPARAPPARG | |
| SCHEMBL11159076 | 0.81 | LMNA (0.36) | LMNACTSKCTSSATMCA1 | |
| SCHEMBL11345065 | 0.79 | MEN1 (0.40) | LMNACTSKCTSSATMCA1 | |
| SCHEMBL10065866 | 0.77 | LMNA (0.51) | LMNAKMT2AMEN1 | |
| SCHEMBL11349885 | 0.76 | PPARA (0.40) | CTSKCTSSPPARAPPARGATM | |
| SCHEMBL11349136 | 0.76 | ACE (0.47) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL26980917 | 0.76 | ACE (0.47) | CTSKCTSSPPARAPPARGACE | |
| SCHEMBL13802716 | 0.76 | SCN9A (0.33) | LMNACTSKCTSS | |
| SCHEMBL13417766 | 0.73 | CTSS (0.38) | CTSKCTSSPPARAPPARGATM | |
| SCHEMBL8680632 | 0.72 | LMNA (0.46) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668781-A | Ceph-3-one compounds and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |
| US-4591642-A | Cephem and cepham derivatives | CIBA-GEIGY CORPORATION (US) | 1986-05-27 | — | — | US | disclosed |
| US-4477658-A | Process for the preparation of cepham and cephem compounds | CIBA-GEIGY CORPORATION (US) | 1984-10-16 | — | — | US | disclosed |
| US-4389524-A | Cepham compounds | CIBA-GEIGY CORPORATION (US) | 1983-06-21 | — | — | US | disclosed |
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |
| US-4089955-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |
| US-4073902-A | ANTIMICROBIAL COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1978-02-14 | — | — | US | disclosed |
| US-3968109-A | ANTIBIOTIC | E. R. SQUIBB & SONS, INC. (US) | 1976-07-06 | — | — | US | disclosed |