Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.73 |
| ▸ | CTSS | P25774 | 1/20 | 0.67 |
| ▸ | CTSK | P43235 | 1/20 | 0.67 |
| ▸ | MME | P08473 | 7/20 | 0.65 |
| ▸ | ACE | P12821 | 4/20 | 0.59 |
| ▸ | CPA1 | P15085 | 4/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.59 |
| ▸ | PAM | P19021 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817100 | 1.00 | GNPAT (0.73) | GNPATCTSSCTSKMMEACE | |
| SCHEMBL6677690 | 1.00 | GNPAT (0.73) | GNPATCTSSCTSKMMEACE | |
| SCHEMBL5692056 | 1.00 | GNPAT (0.73) | GNPATCTSSCTSKMMEACE | |
| Afalanine SCHEMBL8587729 | 0.93 | CTSS (0.65) | GNPATCTSSCTSKMMEACE | |
| Afalanine SCHEMBL158613 | 0.93 | CTSS (0.65) | GNPATCTSSCTSKMMEACE | |
| Afalanine SCHEMBL331330 | 0.93 | CTSS (0.65) | GNPATCTSSCTSKMMEACE | |
| Afalanine SCHEMBL158612 | 0.93 | CTSS (0.65) | GNPATCTSSCTSKMMEACE | |
| SCHEMBL5997104 | 0.93 | MME (0.66) | GNPATCTSSCTSKMMEACE | |
| SCHEMBL15692299 | 0.93 | MME (0.66) | GNPATCTSSCTSKMMEACE | |
| SCHEMBL15692300 | 0.93 | MME (0.66) | GNPATCTSSCTSKMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315843-B1 | ENHANCING ENDOTOXIN DETECTION | BIODTECH INC (US) | 2016-04-20 | — | — | EP | disclosed |
| US-20150152470-A1 | THE USE OF ENDOTOXIN NEUTRALIZATION AS A BIOMARKER FOR INTESTINAL WALL DAMAGE | BioDtech, Inc. | 2015-06-04 | — | — | US | disclosed |
| US-8921063-B2 | Enhancing endotoxin detection | BioDtech, Inc. (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130330759-A1 | ENHANCING ENDOTOXIN DETECTION | BioDtech, Inc. (US) | 2013-12-12 | — | — | US | disclosed |
| US-8349570-B2 | Enhancing endotoxin detection | BioDtech, Inc. (US) | 2013-01-08 | — | — | US | disclosed |
| WO-2012118800-A2 | ENHANCING ENDOTOXIN DETECTION | BioDtech, Inc. (US) | 2012-09-07 | — | — | WO | disclosed |
| WO-2011146463-A2 | ENHANCING ENDOTOXIN DETECTION | BioDtech, Inc. (US) | 2011-11-24 | — | — | WO | disclosed |
| EP-2315843-A2 | ENHANCING ENDOTOXIN DETECTION | Biodtech, Inc. (US) | 2011-05-04 | — | — | EP | disclosed |
| US-20110020854-A1 | Enhancing Endotoxin Detection | BioDtech, Inc. (US) | 2011-01-27 | — | — | US | disclosed |
| US-7846678-B2 | Enhancing endotoxin detection | BioDtech, Inc. (US) | 2010-12-07 | — | — | US | disclosed |
| WO-2010021872-A2 | ENHANCING ENDOTOXIN DETECTION | BioDtech, Inc. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-20100041061-A1 | Enhancing Endotoxin Detection | BioDtech, Inc. (US) | 2010-02-18 | — | — | US | disclosed |
| US-4048305-A | PHENYLALANINE, HISTIDINE | DR. L. ZAMBELETTI S.P.A. (IT) | 1977-09-13 | — | — | US | disclosed |