Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10934656 | 0.99 | KMT2A (0.36) | KMT2AGAATDP1IDH1IDH2 | |
| SCHEMBL3145067 | 0.99 | KMT2A (0.36) | KMT2AGAATDP1IDH1IDH2 | |
| SCHEMBL10912239 | 0.97 | KMT2A (0.32) | KMT2AGAATDP1 | |
| SCHEMBL11031866 | 0.96 | KMT2A (0.34) | KMT2AGAATDP1 | |
| SCHEMBL10910238 | 0.96 | KMT2A (0.34) | KMT2AGAATDP1 | |
| SCHEMBL711948 | 0.91 | GAA (0.37) | KMT2AGAATDP1IDH1IDH2 | |
| SCHEMBL692464 | 0.88 | GAA (0.33) | GAATDP1IDH1IDH2LMNA | |
| SCHEMBL8838277 | 0.86 | — | — | |
| SCHEMBL7481323 | 0.84 | IDH1 (0.34) | GAAIDH1IDH2LMNA | |
| SCHEMBL3145310 | 0.83 | KMT2A (0.36) | KMT2AGAATDP1IDH1IDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075849-B1 | TRIAZINYLLACTAMES, PROCESS FOR THEIR PREPARATION, THEIR USE AS STABILISATORS FOR SYNTHETIC ORGANIC POLYMERS AND POLYMERS STABILISED BY THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |