SCHEMBL10912239

SCHEMBL10912239

CCCCCC(Nc1nc(Cl)nc(Cl)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
GAA P10253 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10910238 0.99 KMT2A (0.34) KMT2AGAATDP1
SCHEMBL11031866 0.99 KMT2A (0.34) KMT2AGAATDP1
SCHEMBL10811643 0.97 KMT2A (0.35) KMT2AGAATDP1
SCHEMBL10934656 0.96 KMT2A (0.36) KMT2AGAATDP1
SCHEMBL3145067 0.96 KMT2A (0.36) KMT2AGAATDP1
SCHEMBL692464 0.91 GAA (0.33) GAATDP1
SCHEMBL711948 0.88 GAA (0.37) KMT2AGAATDP1
SCHEMBL8838277 0.84
SCHEMBL10678358 0.82 ALDH1A1 (0.34)
SCHEMBL7481323 0.81 IDH1 (0.34) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0053775-B1 POLY-BIS-TRIAZYNYL AMINES, PROCESS FOR THEIR PREPARATION, THEIR USE IN STABILISING SYNTHETIC POLYMERS, AND POLYMERS STABILISED THIS WAY HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-07 EP disclosed
EP-0053775-A2 Poly-bis-triazynyl amines, process for their preparation, their use in stabilising synthetic polymers, and polymers stabilised this way HOECHST AKTIENGESELLSCHAFT (DE) 1982-06-16 EP disclosed