SCHEMBL711948

SCHEMBL711948

CCCC(Nc1nc(Cl)nc(NC(CCC)C2CC(C)(C)NC(C)(C)C2)n1)C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
IDH1 O75874 1/20 0.36
IDH2 P48735 1/20 0.36
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.31
SOS1 Q07889 1/20 0.30
NR1I2 O75469 1/20 0.30
AHR P35869 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2C9 P11712 1/20 0.30
NPR3 P17342 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692464 0.97 GAA (0.33) GAATDP1IDH1IDH2LMNA
SCHEMBL7481323 0.93 IDH1 (0.34) GAAIDH1IDH2LMNAKDM4E
SCHEMBL10811643 0.91 KMT2A (0.35) GAATDP1IDH1IDH2LMNA
SCHEMBL3145067 0.90 KMT2A (0.36) GAATDP1IDH1IDH2LMNA
SCHEMBL10934656 0.90 KMT2A (0.36) GAATDP1IDH1IDH2LMNA
SCHEMBL10912239 0.88 KMT2A (0.32) GAATDP1KMT2A
SCHEMBL11451173 0.88 KMT2A (0.33) GAALMNAKMT2A
SCHEMBL10910238 0.87 KMT2A (0.34) GAATDP1KMT2A
SCHEMBL11031866 0.87 KMT2A (0.34) GAATDP1KMT2A
SCHEMBL8838268 0.86 IDH1 (0.31) GAAIDH1IDH2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4225974-A None JP disclosed
US-9963575-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2018-05-08 US disclosed
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2017-04-20 US disclosed
US-9550941-B2 Sterically hindered amine light stabilizers with a mixed functionalization BASF SE (DE) 2017-01-24 US disclosed
EP-2630137-B1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH MIXED FUNCTIONALIZATION BASF SE (DE) 2015-04-01 EP disclosed
US-8830811-B2 Resin composition and optical component MITSUI CHEMICALS, INC. (JP) 2014-09-09 US disclosed
EP-2630137-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH MIXED FUNCTIONALIZATION BASF SE (DE) 2013-08-28 EP disclosed
US-20130207043-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION BASF SE (DE) 2013-08-15 US disclosed
EP-1878769-B1 RESIN COMPOSITION AND OPTICAL COMPONENT MITSUI CHEMICALS INC (JP) 2013-04-17 EP disclosed
US-8354529-B2 Polyamine derivative and polyol derivative BASF SE (DE) 2013-01-15 US disclosed
EP-0314472-A2 Novel piperidyl-triazine derivatives and their use as polymer stabilizers Sankyo Company Limited (JP) 1989-05-03 EP disclosed
US-4760141-A Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1988-07-26 US disclosed
US-4759871-A Stabilizing the polymer from deterioration upon exposure to light and heat ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1988-07-26 US disclosed
US-4740544-A Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1988-04-26 US disclosed
EP-0075849-B1 TRIAZINYLLACTAMES, PROCESS FOR THEIR PREPARATION, THEIR USE AS STABILISATORS FOR SYNTHETIC ORGANIC POLYMERS AND POLYMERS STABILISED BY THEM HOECHST AKTIENGESELLSCHAFT (DE) 1987-07-22 EP disclosed
EP-0209126-A2 Hydrocarbyl(polyphenol)-poly(2,2,6,6-tetramethyl piperidyl-1,3,5-triazines) as stabilizers for synthetic polymer compositions ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-01-21 EP disclosed
US-4504661-A PHOTOSTABILIZERS HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-12 US disclosed
EP-0075849-A2 Triazinyllactames, process for their preparation, their use as stabilisators for synthetic organic polymers and polymers stabilised by them HOECHST AKTIENGESELLSCHAFT (DE) 1983-04-06 EP disclosed
EP-0042554-A1 Polytriazinyl amines, process for their preparation, their use as stabilizing agents for synthetic polymers and polymers stabilized with these compounds HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-30 EP disclosed
US-4234707-A Polymeric light stabilizers for plastics CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130207043-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 GAA 4492/4885TDP1 4246/4885IDH1 3394/4885
US-20170107352-A1 STERICALLY HINDERED AMINE LIGHT STABILIZERS WITH A MIXED FUNCTIONALIZATION C1S, H1-0, H1-2 GAA 4426/4885TDP1 4146/4885IDH1 3469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.