Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.70 |
| ▸ | PPARA | Q07869 | 1/20 | 0.65 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | RGS12 | O14924 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29532272 | 0.86 | KDM4C (0.76) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL611490 | 0.86 | KDM4C (0.76) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL10814853 | 0.83 | KDM4C (0.60) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL29388557 | 0.82 | KDM4C (0.74) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL607997 | 0.82 | KDM4C (0.74) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL29391100 | 0.82 | PPARA (0.92) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL609562 | 0.82 | PPARA (0.92) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL29390264 | 0.82 | KDM4C (0.69) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL607106 | 0.82 | KDM4C (0.69) | KDM4CPPARASTING1ALDH1A1MAPT | |
| SCHEMBL31227881 | 0.81 | PPARA (0.80) | KDM4CPPARASTING1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114734-B1 | PYRIDINYLMETHYLAMINO-ARYLIC ACIDS | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | claimed |
| US-4486593-A | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1984-12-04 | — | — | US | claimed |
| EP-0114734-A2 | Pyridinylmethylamino-arylic acids | THE UPJOHN COMPANY (US) | 1984-08-01 | — | — | EP | claimed |
| EP-0114734-B1 | PYRIDINYLMETHYLAMINO-ARYLIC ACIDS | THE UPJOHN COMPANY (US) | 1987-05-13 | — | — | EP | disclosed |
| US-4486593-A | 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors | THE UPJOHN COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| EP-0114734-A2 | Pyridinylmethylamino-arylic acids | THE UPJOHN COMPANY (US) | 1984-08-01 | — | — | EP | disclosed |