Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817585 | 0.84 | AHR (0.35) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10970412 | 0.78 | AHR (0.34) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL13573561 | 0.75 | AHR (0.40) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL16978978 | 0.75 | RAB9A (0.41) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28988146 | 0.74 | MEN1 (0.38) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10816664 | 0.74 | KDM4E (0.43) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL10812261 | 0.70 | MEN1 (0.34) | AHRMEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL20528659 | 0.70 | AHR (0.37) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL17970848 | 0.69 | RAB9A (0.44) | AHRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL12639170 | 0.68 | MEN1 (0.45) | MEN1KMT2AALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087326-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYCOMED AS (NO) | 1987-05-13 | — | — | EP | disclosed |
| US-4539324-A | ANTICANCER AGENTS | NYEGAARD & CO. A/S (NO) | 1985-09-03 | — | — | US | disclosed |
| EP-0087326-A1 | Substituted pyrimidin-2-ones and the salts thereof | NYCOMED AS (NO) | 1983-08-31 | — | — | EP | disclosed |