Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10818075 | 0.75 | RXRA (0.39) | KMT2ATHRB | |
| SCHEMBL10817585 | 0.73 | AHR (0.35) | MEN1KMT2AAHRALDH1A1MAPT | |
| SCHEMBL11018085 | 0.72 | RXRA (0.41) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL10815798 | 0.71 | HTT (0.39) | MEN1KMT2AMAPTHPGD | |
| SCHEMBL10812971 | 0.70 | AHR (0.33) | MEN1KMT2AAHRALDH1A1MAPT | |
| SCHEMBL10970412 | 0.70 | AHR (0.34) | MEN1KMT2AAHRALDH1A1MAPT | |
| SCHEMBL10811050 | 0.70 | EGLN1 (0.43) | MEN1KMT2AMAPT | |
| SCHEMBL13573561 | 0.69 | AHR (0.40) | MEN1KMT2AAHRALDH1A1MAPT | |
| SCHEMBL10816686 | 0.69 | L3MBTL1 (0.43) | ALDH1A1HPGD | |
| SCHEMBL10813483 | 0.68 | EGLN1 (0.43) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0087326-B1 | SUBSTITUTED PYRIMIDIN-2-ONES AND THE SALTS THEREOF | NYCOMED AS (NO) | 1987-05-13 | — | — | EP | disclosed |
| US-4539324-A | ANTICANCER AGENTS | NYEGAARD & CO. A/S (NO) | 1985-09-03 | — | — | US | disclosed |
| EP-0087326-A1 | Substituted pyrimidin-2-ones and the salts thereof | NYCOMED AS (NO) | 1983-08-31 | — | — | EP | disclosed |