Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.72 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071813 | 0.99 | ADORA1 (0.76) | ADORA1ADORA2BRXFP1MAPK1LMNA | |
| SCHEMBL10861746 | 0.99 | ADORA1 (0.76) | ADORA1ADORA2BRXFP1MAPK1LMNA | |
| SCHEMBL10861102 | 0.97 | ADORA1 (0.74) | ADORA1ADORA2BRXFP1MAPK1LMNA | |
| SCHEMBL10856181 | 0.92 | ADORA2B (0.76) | ADORA1ADORA2BRXFP1MAPK1LMNA | |
| SCHEMBL16120975 | 0.90 | ADORA2B (0.88) | ADORA1ADORA2BRXFP1MAPK1LMNA | |
| SCHEMBL11477657 | 0.89 | ADORA1 (0.61) | ADORA1ADORA2BRXFP1MAPK1LMNA | |
| SCHEMBL16120983 | 0.88 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120999 | 0.88 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120982 | 0.88 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT | |
| SCHEMBL16120989 | 0.88 | ADORA2B (0.85) | ADORA2BRXFP1MAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4713455-A | FOR OBSTRUCTIVE DISORDERS OF THE RESPIRATORY TRACT | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | disclosed |
| US-4616020-A | TREATING OBSTRUCTIVE RESPIRATORY DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | disclosed |
| US-4576947-A | HYDROXYALKYLXANTHINES, INCREASING CEREBRAL BLOOD FLOW, BRONCHODILATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| EP-0075850-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING VICINAL DIHYDROXYALKYL XANTHINES, PROCESS FOR THE PREPARATION OF THE XANTHINES AND THE APPROPRIATE INTERMEDIATES THEREFOR | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-12-18 | — | — | EP | disclosed |
| EP-0075850-A2 | Pharmaceutical preparations containing vicinal dihydroxyalkyl xanthines, process for the preparation of the xanthines and the appropriate intermediates therefor | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-06 | — | — | EP | disclosed |
| US-4207321-A | PROMOTES BLOOD PERFUSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |