Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 13/20 | 0.76 |
| ▸ | PDE4A | P27815 | 2/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.74 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.74 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10813433 | 0.92 | ADORA1 (0.74) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10861102 | 0.92 | ADORA1 (0.74) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8071813 | 0.90 | ADORA1 (0.76) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10861746 | 0.90 | ADORA1 (0.76) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL316279 | 0.87 | ADORA2B (1.00) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10354149 | 0.87 | ADORA2B (0.68) | ADORA2BADORA1LMNAMAPTALDH1A1 | |
| SCHEMBL16120984 | 0.86 | ADORA2B (0.81) | ADORA2BADORA2AADORA1LMNAMAPT | |
| SCHEMBL11462233 | 0.85 | PDE4A (0.81) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL15453295 | 0.83 | ADORA2B (0.72) | ADORA2BADORA2AADORA1LMNAMAPT | |
| SCHEMBL16120979 | 0.83 | ADORA2B (0.85) | ADORA2BADORA2AADORA1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4576947-A | HYDROXYALKYLXANTHINES, INCREASING CEREBRAL BLOOD FLOW, BRONCHODILATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| US-4207321-A | PROMOTES BLOOD PERFUSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |