Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | POLG | P54098 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17758901 | 0.81 | BLM (0.63) | CYP3A4POLG | |
| SCHEMBL10601866 | 0.79 | ENPP1 (0.53) | ENPP1NT5ECYP3A4ADORA2AADORA1 | |
| SCHEMBL10813839 | 0.78 | ADORA2A (0.50) | CYP3A4ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL22193337 | 0.78 | FGFR1 (0.57) | ENPP1CYP3A4ADORA2AADORA1FGFR1 | |
| SCHEMBL8846475 | 0.77 | ADORA2A (0.56) | CYP3A4ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL10818140 | 0.76 | ADORA2A (0.50) | CYP3A4ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL30292318 | 0.75 | ADORA2A (0.64) | CYP3A4ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL4093935 | 0.75 | ADORA2A (0.64) | CYP3A4ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL20930041 | 0.75 | AHCY (0.54) | ENPP1ADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL18715785 | 0.74 | CYP3A4 (0.61) | CYP3A4FGFR1SLC22A6CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160138029-A1 | ANTISENSE-OLIGONUCLEOTIDES AS INHIBITORS OF TGF-R SIGNALING | Neurovision Pharma GmbH (DE) | 2016-05-19 | — | — | US | disclosed |