Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10805978 | 0.91 | POLR1A (0.37) | PARP1 | |
| SCHEMBL10805040 | 0.90 | PARP1 (0.36) | PARP1 | |
| Hydrochloric Acid SCHEMBL10804235 | 0.87 | PARP1 (0.32) | PARP1 | |
| Hydrochloric Acid SCHEMBL10810418 | 0.86 | PARP1 (0.32) | PARP1 | |
| SCHEMBL10812102 | 0.86 | PARP1 (0.32) | PARP1 | |
| SCHEMBL9822902 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL10807647 | 0.80 | POLR1A (0.38) | PARP1 | |
| SCHEMBL11116671 | 0.79 | PARP1 (0.32) | PARP1 | |
| Hydrochloric Acid SCHEMBL10808407 | 0.78 | PNMT (0.36) | PARP1 | |
| Hydrochloric Acid SCHEMBL10811463 | 0.78 | BRD4 (0.36) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124783-B1 | BENZOFURAN- AND BENZOPYRAN-CARBOXAMIDE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-12-09 | — | — | EP | disclosed |
| US-4617314-A | Benzofuran- and benzopyran-carboxamide derivatives | YOSHITOMI PHARMACEUTICAL INDUSTRIES LTD. (JP) | 1986-10-14 | — | — | US | disclosed |