Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762944 | 0.82 | CHRM2 (0.38) | CNR1TSHRGAAMAPTSMN1; SMN2 | |
| SCHEMBL28780403 | 0.82 | CYP19A1 (0.38) | TRPA1CNR1GAAKDM4EMAPT | |
| SCHEMBL27762947 | 0.82 | CYP19A1 (0.43) | — | |
| SCHEMBL27762945 | 0.82 | CHRM2 (0.38) | CNR1TSHRGAAMAPTSMN1; SMN2 | |
| SCHEMBL10505285 | 0.79 | — | — | |
| SCHEMBL10146248 | 0.79 | — | — | |
| SCHEMBL10513500 | 0.79 | CPB2 (0.36) | TSHRNAPRTGAAKDM4EMAPT | |
| SCHEMBL5851068 | 0.78 | FFAR1 (0.42) | CNR1TSHRSMN1; SMN2 | |
| SCHEMBL11019672 | 0.77 | TRPA1 (0.38) | TRPA1CNR1NAPRTGAAKDM4E | |
| SCHEMBL28854086 | 0.77 | TRPA1 (0.38) | TRPA1CNR1NAPRTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122693-B1 | ANTIFUNGAL DI(AZOLYL)PROPANOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-08 | — | — | EP | disclosed |
| EP-0122693-A1 | Antifungal di(azolyl)propanol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-24 | — | — | EP | disclosed |