Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815403 | 1.00 | KMT2A (0.39) | KMT2AHTTMAPTALDH1A1MEN1 | |
| SCHEMBL4622526 | 0.84 | ACHE (0.46) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10812092 | 0.84 | KMT2A (0.38) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10812089 | 0.84 | KMT2A (0.38) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL7818824 | 0.81 | KMT2A (0.43) | KMT2AHTTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7818827 | 0.81 | KMT2A (0.43) | KMT2AHTTMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4016019 | 0.80 | KMT2A (0.47) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL10816594 | 0.77 | KMT2A (0.37) | KMT2AHTTMAPTALDH1A1MEN1 | |
| SCHEMBL10816599 | 0.77 | KMT2A (0.37) | KMT2AHTTMAPTALDH1A1MEN1 | |
| SCHEMBL10930017 | 0.76 | KMT2A (0.47) | KMT2AHTTMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118565-B1 | 1,4-METHANO-2-BENZAZEPINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-05-27 | — | — | EP | disclosed |
| US-4546107-A | 1,4-Methano-2-benzazepine derivatives useful as cerebal dysfunction-improving drugs, anti-convulsant, anti-epileptic or anti-anxiety drugs | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1985-10-08 | — | — | US | disclosed |
| EP-0118565-A1 | 1,4-METHANO-2-BENZAZEPINE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1984-09-19 | — | — | EP | disclosed |