Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033455 | 0.88 | MAPT (0.43) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL29958397 | 0.88 | MAPT (0.43) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL24214577 | 0.88 | FAAH (0.43) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2464708 | 0.85 | KMT2A (0.48) | KMT2ACA1CA2 | |
| SCHEMBL16595273 | 0.84 | P2RX7 (0.41) | KMT2AMAPTP2RX7SMN1; SMN2MEN1 | |
| SCHEMBL29174247 | 0.83 | CYP1A2 (0.40) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL11378329 | 0.83 | RAB9A (0.56) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL29992013 | 0.82 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1ALDH1A1SLC6A4 | |
| SCHEMBL5859196 | 0.81 | KMT2A (0.48) | KMT2AMAPTALDH1A1 | |
| SCHEMBL18989955 | 0.80 | KMT2A (0.47) | KMT2ACA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598417-B2 | Analgesics; muscular disorders; diarrhea | ALLERGAN, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-20080255239-A1 | SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS | ALLERGAN, INC. | 2008-10-16 | — | — | US | disclosed |
| EP-0056271-B1 | CARBOXYLIC ACID ESTERS AND INSECTICIDAL AND/OR ACARICIDAL COMPOSITIONS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4480118-A | Carboxylic acid ester and an insecticidal and/or acaricidal composition containing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0056271-A2 | Carboxylic acid esters and insecticidal and/or acaricidal compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255239-A1 | SUBSTITUTED FLUOROETHYL UREAS AS ALPHA 2 ADRENERGIC AGENTS | ADRB2, ADRA2A, ADRA2C | KMT2A 1449/4885MAPT 433/4885P2RX7 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.