Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10808538 | 0.76 | NPSR1 (0.79) | NPSR1MAPTHPGDDCUN1D1ALDH1A1 | |
| SCHEMBL21176923 | 0.75 | MAPT (0.47) | NPSR1MAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL10812182 | 0.73 | NPSR1 (0.54) | NPSR1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6668805 | 0.73 | SCN9A (0.49) | NPSR1HSP90AA1MAPTHPGDALDH1A1 | |
| SCHEMBL10810550 | 0.72 | NPSR1 (0.53) | NPSR1KMT2AKDM4EMEN1PTGS1 | |
| SCHEMBL10638768 | 0.72 | BRD4 (0.49) | NPSR1MAPTSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL10814788 | 0.71 | NPSR1 (0.56) | NPSR1HSP90AA1MAPTHPGDDCUN1D1 | |
| SCHEMBL11337060 | 0.71 | ALDH1A1 (0.50) | NPSR1HSP90AA1MAPTHPGDHSD11B1 | |
| SCHEMBL10816529 | 0.71 | NPSR1 (0.51) | NPSR1HSP90AA1MAPTHPGDALDH1A1 | |
| SCHEMBL14665605 | 0.70 | NPSR1 (0.46) | NPSR1MAPTHPGDALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077983-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-29 | — | — | EP | disclosed |
| US-4616014-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0077983-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-04 | — | — | EP | disclosed |