Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847185 | 0.84 | NPSR1 (0.56) | NPSR1ADORA2AADORA1KDM4EKMT2A | |
| SCHEMBL14665605 | 0.84 | NPSR1 (0.46) | NPSR1ADORA2AADORA1KDM4EKMT2A | |
| SCHEMBL10812182 | 0.81 | NPSR1 (0.54) | NPSR1ADORA2AADORA1KDM4EKMT2A | |
| SCHEMBL10808538 | 0.80 | NPSR1 (0.79) | NPSR1ADORA2AADORA1KDM4EKMT2A | |
| SCHEMBL4517048 | 0.79 | KDM4E (0.51) | NPSR1ADORA2AADORA1KDM4EKMT2A | |
| SCHEMBL10812882 | 0.76 | NPSR1 (0.67) | NPSR1ADORA2AADORA1KDM4EKMT2A | |
| SCHEMBL4504538 | 0.75 | ALDH1A1 (0.47) | ADORA2AADORA1KDM4EKMT2AMEN1 | |
| SCHEMBL10810284 | 0.75 | ADORA1 (0.48) | ADORA2AADORA1KDM4EPTGS1PTGS2 | |
| SCHEMBL10812733 | 0.74 | ADORA2A (0.47) | ADORA2AADORA1KMT2AMEN1PTGS1 | |
| SCHEMBL11114941 | 0.73 | ALDH1A1 (0.62) | NPSR1KDM4EIDO1AURKAKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077983-B1 | TRIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-29 | — | — | EP | disclosed |
| US-4616014-A | HYPOTENSIVE AGENTS, ANTICOAGULANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0077983-A1 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-05-04 | — | — | EP | disclosed |