Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266855 | 0.72 | ALDH1A1 (0.38) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL10737675 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HPGDRXFP1MEN1KMT2A | |
| SCHEMBL20226284 | 0.69 | ALDH1A1 (0.36) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL6844725 | 0.66 | TNKS2 (0.45) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL15604879 | 0.65 | — | — | |
| SCHEMBL18125709 | 0.65 | CYP2C19 (0.45) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL1316915 | 0.65 | MEN1 (0.44) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL11812669 | 0.65 | CYP2C19 (0.45) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL13834469 | 0.64 | KMT2A (0.68) | ALDH1A1MEN1KMT2ANPC1TNKS2 | |
| SCHEMBL9875845 | 0.64 | KMT2A (0.50) | ALDH1A1HPGDMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111073-B1 | PROCESS FOR THE PREPARATION OF 2-IMIDAZOLINES | BASF Aktiengesellschaft (DE) | 1987-02-25 | — | — | EP | disclosed |
| EP-0111073-A1 | Process for the preparation of 2-imidazolines | BASF Aktiengesellschaft (DE) | 1984-06-20 | — | — | EP | disclosed |