Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.35 |
| ▸ | SELE | P16581 | 5/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10804514 | 0.90 | SLC2A1 (0.40) | SLC2A1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL10805234 | 0.72 | SLC2A1 (0.74) | SLC2A1HAO1NPC1SMN1; SMN2MEN1 | |
| SCHEMBL20272422 | 0.71 | SLC2A1 (0.47) | SLC2A1MEN1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL28153083 | 0.69 | HAO1 (0.46) | HAO1NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6850243 | 0.68 | SLC2A1 (0.44) | SLC2A1CYP1A2KMT2AHTTPTK2 | |
| SCHEMBL10803369 | 0.68 | SLC2A1 (0.44) | SLC2A1RAB9AMEN1ALDH1A1KMT2A | |
| SCHEMBL6850410 | 0.68 | HTT (0.47) | SLC2A1ALDH1A1HTTPTK2 | |
| SCHEMBL18879034 | 0.66 | SLC2A1 (0.56) | SLC2A1CYP3A4KDM4EHTTPTK2 | |
| SCHEMBL10801863 | 0.63 | SLC2A1 (0.70) | SLC2A1NPC1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL10804993 | 0.63 | SLC2A1 (0.49) | SLC2A1SMN1; SMN2MEN1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | claimed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | claimed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | claimed |
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | disclosed |