Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GNG2 | P59768 | 1/20 | 0.34 |
| ▸ | GNB1 | P62873 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20272422 | 0.80 | SLC2A1 (0.47) | SLC2A1HTTPTK2MAPTALDH1A1 | |
| SCHEMBL6850243 | 0.77 | SLC2A1 (0.44) | SLC2A1HTTPTK2MAPTNR4A2 | |
| SCHEMBL6850410 | 0.77 | HTT (0.47) | SLC2A1HTTPTK2MAPTALDH1A1 | |
| SCHEMBL18879034 | 0.74 | SLC2A1 (0.56) | SLC2A1HTTPTK2MAPTTERT | |
| SCHEMBL7572921 | 0.71 | MAPT (0.47) | HTTPTK2MAPTCHEK1ALDH1A1 | |
| SCHEMBL10803018 | 0.70 | SLC2A1 (0.52) | SLC2A1NCF1HTTPTK2MAPT | |
| SCHEMBL10817816 | 0.70 | SLC2A1 (0.59) | SLC2A1HTTPTK2MAPTPOLB | |
| SCHEMBL23841035 | 0.69 | NCF1 (0.43) | NCF1HTTMAPTNR4A2CHEK1 | |
| SCHEMBL10816834 | 0.68 | SLC2A1 (0.41) | SLC2A1HTTPTK2ALDH1A1MEN1 | |
| SCHEMBL10806175 | 0.68 | NPY5R (0.53) | SLC2A1NCF1HTTPTK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | claimed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | claimed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | claimed |
| US-20170145009-A1 | HETEROCYCLIC COMPOUNDS THAT INHIBIT THE KINASE ACTIVITY OF MNK USEFUL FOR TREATING VARIOUS CANCERS | EFFECTOR THERAPEUTICS, INC. | 2017-05-25 | — | — | US | disclosed |
| US-4680307-A | Carbacyclin analogs | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-07-14 | — | — | US | disclosed |
| EP-0119774-B1 | ANTI-INFLAMMATORY PYRAZOLO PYRIDINES | BEECHAM GROUP PLC (GB) | 1987-06-24 | — | — | EP | disclosed |
| US-4559348-A | SKIN DISORDERS | BEECHAM GROUP, P.L.C. (GB) | 1985-12-17 | — | — | US | disclosed |
| EP-0119774-A1 | Anti-inflammatory pyrazolo pyridines | BEECHAM GROUP PLC (GB) | 1984-09-26 | — | — | EP | disclosed |
| EP-0115954-A2 | Bicyclooctane derivatives and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145009-A1 | HETEROCYCLIC COMPOUNDS THAT INHIBIT THE KINASE ACTIVITY OF MNK USEFUL FOR TREATING VARIOUS CANCERS | MAP3K9, MAP3K19, MAP3K20 | SLC2A1 3888/4885NCF1 959/4885HTT 4376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.