⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139652 | 0.86 | — | — | |
| SCHEMBL7172295 | 0.84 | MAOA (0.42) | — | |
| SCHEMBL1680340 | 0.80 | — | — | |
| SCHEMBL19217600 | 0.79 | — | — | |
| SCHEMBL7003873 | 0.79 | GPR84 (0.41) | — | |
| SCHEMBL79201 | 0.78 | MAOA (0.47) | — | |
| SCHEMBL25422764 | 0.77 | — | — | |
| SCHEMBL8955030 | 0.77 | GPR84 (0.44) | — | |
| SCHEMBL1231893 | 0.76 | — | — | |
| SCHEMBL6284681 | 0.76 | MAOA (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114632-B1 | 5-(4-VINYL- OR 4-ETHYNYLBENZOYL)-1,2-DIHYDRO-3H-PYRROLO-(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | SYNTEX (U.S.A.) INC. (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4560699-A | ANTIPYRETICS, ANTICOAGULANTS, VASODILAAORS, MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0041711-B1 | 6-CHLORO- OR 6-BROMO-1,2-DIHYDRO-3H-PYRROLO(1,2-A)-PYRROLE-1-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYNTEX (U.S.A.) INC. (US) | 1985-04-17 | — | — | EP | disclosed |
| EP-0114632-A1 | 5-(4-Vinyl- or 4-ethynylbenzoyl)-1,2-dihydro-3H-pyrrolo-(1,2-A)-pyrrole-1-carboxylic acids and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1984-08-01 | — | — | EP | disclosed |
| US-4344943-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1982-08-17 | — | — | US | disclosed |
| EP-0041711-A1 | 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo(1,2-a)-pyrrole-1-carboxylic acids and derivatives thereof, process for their production and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1981-12-16 | — | — | EP | disclosed |