Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.49 |
| ▸ | LPAR5 | Q9H1C0 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690257 | 0.84 | ALDH1A1 (0.59) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL17521526 | 0.83 | LPAR1 (0.51) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL1746823 | 0.81 | LTA4H (0.60) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL507354 | 0.81 | ST14 (0.52) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL1582083 | 0.81 | LPAR1 (0.49) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL9502693 | 0.81 | TTR (0.50) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL11604236 | 0.79 | SLC6A4 (0.54) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL172615 | 0.78 | HTR2A (0.55) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL28816731 | 0.78 | LTA4H (0.55) | LPAR1LPAR5ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL3520758 | 0.78 | PARP10 (0.51) | LPAR1LPAR5NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |