SCHEMBL1081737

SCHEMBL1081737

CCN(C=O)C(O)[C@H]1O[C@@H](n2cnc3c(N)nc(NCCc4ccc(CCC(=O)O)cc4)nc32)[C@H](O)[C@@H]1O

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ADORA2A P29274 10/20 0.68
▸ ADORA3 P0DMS8 7/20 0.68
▸ ADORA1 P30542 7/20 0.68
▸ ADORA2B P29275 4/20 0.68
▸ KDM4E B2RXH2 3/20 0.68
▸ ALOX15 P16050 2/20 0.68
▸ HSD17B10 Q99714 2/20 0.68
▸ KMT2A Q03164 2/20 0.68
▸ TSHR P16473 1/20 0.68
▸ MEN1 O00255 1/20 0.68
▸ ALDH1A1 P00352 1/20 0.68
▸ CYP2D6 P10635 1/20 0.68
▸ CYP2C19 P33261 1/20 0.68
▸ PMP22 Q01453 1/20 0.67
▸ ATM Q13315 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6754869 0.99 ADORA2A (0.68) ADORA2AADORA3ADORA1ADORA2BKDM4E
Hydrochloric Acid SCHEMBL2031971 0.99 ADORA2A (0.67) ADORA2AADORA3ADORA1ADORA2BKDM4E
SCHEMBL2295172 0.93 ADORA2A (0.65) ADORA2AADORA3ADORA1ADORA2BKDM4E
SCHEMBL1976908 0.91 ADORA2A (0.56) ADORA2AADORA3ADORA1ADORA2BKDM4E
SCHEMBL724837 0.91 ADORA2A (0.58) ADORA2AADORA3ADORA1ADORA2BKDM4E
SCHEMBL940189 0.89 ADORA2A (0.55) ADORA2AADORA3ADORA1ADORA2BKDM4E
Hydrochloric Acid SCHEMBL9247444 0.89 ADORA2A (0.70) ADORA2AADORA3ADORA1ADORA2BKDM4E
SCHEMBL22533842 0.85 ADORA2A (0.72) ADORA2AADORA3ADORA1ADORA2BKDM4E
Hydrochloric Acid SCHEMBL23859924 0.85 ADORA2A (0.71) ADORA2AADORA3ADORA1ADORA2BKDM4E
SCHEMBL5490949 0.82 ADORA2A (0.73) ADORA2AADORA3ADORA1ADORA2BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024243-A1 Fine Dry Particulate Adenosine Compositions and Topical Formulations Including the Same LABORATORY SKIN CARE, INC. 2024-01-25 — — US claimed
EP-2204154-B1 Association of monosaccharides and adenosine and its cosmetic use ORÉAL L (FR) 2016-10-12 — — EP claimed
EP-2204154-A1 Association of monosaccharides and adenosine and its cosmetic use L'OREAL (FR) 2010-07-07 — — EP claimed
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF L'OREAL (FR) 2010-07-01 — — US claimed
US-20070232560-A1 Treatment of skin with adenosine or adenosine analog UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION 2007-10-04 — — US claimed
EP-1424064-B1 Use of adenosin or an adenosin analog to smooth out fine lines OREAL (FR) 2007-06-06 — — EP claimed
WO-2007042679-A2 COSMETIC COMPOSITION CONTAINING A NON-PHOSPHATE COMPOUND BASED ON ADENOSINE AND A TIGHTENING POLYMER L'OREAL (FR) 2007-04-19 — — WO claimed
US-20060240056-A1 Treatment of skin with adenosine or adenosine analog UNIVERSITY OF MASSACHUSETTS, A MASSACHUSETTS CORPORATION 2006-10-26 — — US claimed
US-20060099568-A1 Signals and molecular species involved in senescence SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2006-05-11 — — US claimed
EP-1014995-A4 COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSIS FOLLOWING REVASCULARIZATION PROCEDURES ADERIS PHARMACEUTICALS INC (US) 2005-02-16 — — EP claimed
JP-2002505687-A — — 2002-02-19 — — JP claimed
EP-0589964-B1 METHOD AND COMPOSITION TO REDUCE MYOCARDIAL REPERFUSION INJURY UNIV VANDERBILT (US) 2001-12-12 — — EP claimed
EP-0880353-A4 COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION THERASYS INC (US) 2001-04-18 — — EP claimed
EP-1014995-A1 COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSIS FOLLOWING REVASCULARIZATION PROCEDURES Discovery Therapeutics, Inc. (US) 2000-07-05 — — EP claimed
US-5998423-A IN SKIN OR HAIR; ADMINISTERING ADENOSINE RECEPTOR ANTAGONIST THERASYS, INC. (US) 1999-12-07 — — US claimed
WO-1998057651-A1 COMPOSITIONS AND METHODS FOR PREVENTING RESTENOSIS FOLLOWING REVASCULARIZATION PROCEDURES DISCOVERY THERAPEUTICS, INC. (US) 1998-12-23 — — WO claimed
EP-0880353-A1 COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION Therasys, Inc. (US) 1998-12-02 — — EP claimed
WO-1998015276-A1 COMPOSITIONS AND METHODS FOR MODULATING MELANIN PRODUCTION THERASYS, INC. (US) 1998-04-16 — — WO claimed
US-5424297-A Adenosine dextran conjugates UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) 1995-06-13 — — US claimed
US-5206222-A Coadministering adenosine or an analog and lidocaine VANDERBILT UNIVERSITY (US) 1993-04-27 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168049-A1 COMBINATION OF MONOSACCHARIDES AND ADENOSINE AND USE THEREOF ADORA2A, ADORA1, ADORA3 ADORA2A 1/4885ADORA3 3/4885ADORA1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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