Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.48 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10788223 | 0.81 | MEN1 (0.58) | LMNAMEN1KMT2APDK1PDK2 | |
| SCHEMBL10811275 | 0.79 | CA1 (0.32) | CXCL8LMNAPDK1CYP1A2KDM4E | |
| SCHEMBL10815320 | 0.77 | CA1 (0.34) | — | |
| SCHEMBL1439894 | 0.77 | TYK2 (0.52) | CXCL8TYK2LMNAMEN1KMT2A | |
| SCHEMBL11449076 | 0.76 | XIAP (0.52) | CXCL8TYK2LMNAMEN1KMT2A | |
| SCHEMBL12780363 | 0.76 | CXCL8 (0.49) | CXCL8TYK2LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8974695 | 0.75 | XIAP (0.51) | CXCL8TYK2LMNAMEN1KMT2A | |
| SCHEMBL10816887 | 0.75 | ALDH1A1 (0.45) | LMNAMEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL10787070 | 0.73 | POLB (0.57) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL10816152 | 0.73 | NPC1 (0.60) | LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698333-A | Use of substituted malonic acid derivatives as agents for combating pests | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-06 | — | — | US | disclosed |
| EP-0076957-B1 | DIAMIDES OF SUBSTITUTED HYDROXYMALONIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-04-09 | — | — | EP | disclosed |
| US-4562185-A | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-31 | — | — | US | disclosed |
| US-4556649-A | Substituted malonic acid diamide insecticides, compositions and use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |
| EP-0148499-A2 | Substituted derivatives of malonic acid, process for their preparation and their use as pesticides | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |
| EP-0108351-A2 | Use of substituted malonic-acid derivatives as pesticides | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |
| EP-0076957-A1 | Diamides of substituted hydroxymalonic acids, process for their preparation and their use as pesticides | BAYER AG (DE) | 1983-04-20 | — | — | EP | disclosed |