Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.62 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrocortisone SCHEMBL3706525 | 0.90 | G6PD (0.73) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL16833654 | 0.89 | G6PD (0.72) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL7857249 | 0.89 | G6PD (0.74) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL9788966 | 0.89 | G6PD (0.62) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL23037583 | 0.88 | G6PD (0.66) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL14784945 | 0.88 | G6PD (0.66) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL4335304 | 0.88 | G6PD (0.62) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL14843416 | 0.88 | G6PD (0.76) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL1184192 | 0.88 | G6PD (0.79) | G6PDCYP3A4GABRA1GABRB2GABRG2 | |
| Tetrahydrocortisone SCHEMBL5610354 | 0.88 | G6PD (0.79) | G6PDCYP3A4GABRA1GABRB2GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210025-A2 | 5-Substituted-6-aminopyrimidine derivatives, composition and uses | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-01-28 | — | — | EP | disclosed |