SCHEMBL10818151

SCHEMBL10818151

O=C(/C=C/C(=O)OC1CNCCO1)OC1CNCCO1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 2/20 0.34
REN P00797 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1532787 0.86 SSTR4 (0.33) SSTR4
SCHEMBL7357398 0.81 SSTR4 (0.36) SSTR4
SCHEMBL9207735 0.79 SSTR4 (0.38) SSTR4REN
SCHEMBL2445619 0.79 SSTR4 (0.35) SSTR4
SCHEMBL28781524 0.79 SLC6A2 (0.35) SSTR4
Hydrochloric Acid SCHEMBL23277053 0.78 SSTR4 (0.37) SSTR4
Hydrochloric Acid SCHEMBL20599528 0.78 SSTR4 (0.37) SSTR4
SCHEMBL7276009 0.76 SSTR4 (0.39) SSTR4REN
SCHEMBL7907555 0.75 SSTR4 (0.35) SSTR4
SCHEMBL1655321 0.75 SSTR4 (0.38) SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698430-A ANTIDEPRESSANT A. H. ROBINS COMPANY, INC. (US) 1987-10-06 US disclosed