Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.37 |
| ▸ | SYK | P43405 | 4/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402274 | 0.81 | ADORA2B (0.60) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1063583 | 0.79 | ADORA2B (0.44) | ADORA2BADORA2ASYKFLT3 | |
| SCHEMBL1081900 | 0.75 | ADORA2B (0.67) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1065067 | 0.74 | ADORA2A (0.44) | ADORA2BADORA2ASYKFLT3 | |
| SCHEMBL1065584 | 0.73 | ADORA2B (0.60) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1065068 | 0.73 | ADORA2B (0.60) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1081716 | 0.73 | ADORA2B (0.58) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4406115 | 0.72 | ADORA2B (0.59) | ADORA2BADORA2AADORA1 | |
| SCHEMBL1063503 | 0.71 | ADORA2A (0.50) | ADORA2BADORA2A | |
| SCHEMBL1061344 | 0.69 | ADORA2B (0.43) | ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268641-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | Advinus Therapeutics Pvt. Ltd. (IN) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009118759-A2 | HETEROCYCLIC COMPOUNDS AS ADENOSINE RECEPTOR ANTAGONIST | ADVINUS THERAPEUTICS PVT. LTD., (IN) | 2009-10-01 | — | — | WO | disclosed |