Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667862 | 0.86 | NPSR1 (0.59) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL6469548 | 0.78 | HTR2C (0.60) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL7292049 | 0.76 | NPSR1 (0.55) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| Bromide SCHEMBL10821179 | 0.76 | HTR2C (0.48) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL8205708 | 0.75 | HTR2C (0.57) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL2494144 | 0.74 | HTR2C (0.52) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL7289880 | 0.74 | NPSR1 (0.59) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL29414816 | 0.74 | HTR2C (0.55) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL6516528 | 0.74 | HTR2C (0.55) | NPSR1HTR2CHTR1AHTR2AHTR2B | |
| SCHEMBL9536748 | 0.74 | NPSR1 (0.56) | NPSR1HTR2CHTR1AHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4604386-A | CONTROL OF GRAMPOSITIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0168222-A2 | 3-(Alkynylalkyloxy) Cephalosporins | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |