SCHEMBL1667862

SCHEMBL1667862

NC(C(=O)O)c1c[nH]c2ccc(O)cc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPSR1 Q6W5P4 6/20 0.59
▸ HTR2C P28335 5/20 0.59
▸ CYP3A4 P08684 4/20 0.59
▸ HTR1A P08908 4/20 0.59
▸ HTR2A P28223 4/20 0.59
▸ HTR2B P41595 4/20 0.59
▸ ALDH1A1 P00352 4/20 0.59
▸ NFKB1 P19838 3/20 0.59
▸ TSHR P16473 3/20 0.59
▸ LMNA P02545 3/20 0.59
▸ BLM P54132 3/20 0.59
▸ MAPT P10636 3/20 0.59
▸ KDM4E B2RXH2 3/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ PMP22 Q01453 2/20 0.59
▸ HTR7 P34969 2/20 0.59
▸ ADORA3 P0DMS8 1/20 0.59
▸ ALOX15 P16050 1/20 0.59
▸ SLC6A4 P31645 1/20 0.59
▸ MTOR P42345 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10821180 0.86 NPSR1 (0.51) NPSR1HTR2CCYP3A4HTR1AHTR2A
SCHEMBL7292049 0.84 NPSR1 (0.55) NPSR1HTR2CCYP3A4HTR1AHTR2A
SCHEMBL2494144 0.81 HTR2C (0.52) NPSR1HTR2CCYP3A4HTR1AHTR2A
SCHEMBL9536748 0.81 NPSR1 (0.56) NPSR1HTR2CCYP3A4HTR1AHTR2A
SCHEMBL30518932 0.79 MEN1 (0.56) HTR2CHTR2AHTR2BALDH1A1TSHR
SCHEMBL6469548 0.79 HTR2C (0.60) NPSR1HTR2CCYP3A4HTR1AHTR2A
SCHEMBL30518090 0.79 MEN1 (0.56) HTR2CHTR2AHTR2BALDH1A1TSHR
SCHEMBL1349263 0.79 MEN1 (0.56) HTR2CHTR2AHTR2BALDH1A1TSHR
SCHEMBL10079616 0.79 MEN1 (0.56) HTR2CHTR2AHTR2BALDH1A1TSHR
SCHEMBL7289880 0.78 NPSR1 (0.59) NPSR1HTR2CCYP3A4HTR1AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118011-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-14 — — US disclosed
EP-3461855-B1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES UNIV RUTGERS (US) 2020-05-27 — — EP disclosed
US-20190185624-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-06-20 — — US disclosed
EP-3461855-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2019-04-03 — — EP disclosed
US-10202490-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-02-12 — — US disclosed
EP-2486081-B1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES UNIV RUTGERS (US) 2018-12-05 — — EP disclosed
US-20170158819-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2017-06-08 — — US disclosed
US-9605112-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-28 — — US disclosed
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-09-06 — — US disclosed
EP-2486081-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES Rutgers, The State University of New Jersey (US) 2012-08-15 — — EP disclosed
WO-2011044567-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-04-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES MATR3, MIF, BMP2 NPSR1 1710/4885HTR2C 4306/4885CYP3A4 3629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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