Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.56 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | HTR2A | P28223 | 5/20 | 0.56 |
| ▸ | HTR2B | P41595 | 5/20 | 0.56 |
| ▸ | HTR1A | P08908 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28422454 | 0.86 | NPSR1 (0.55) | NPSR1HTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL11265914 | 0.84 | F7 (0.54) | HTR2AMAPTKMT2AMEN1PKM | |
| SCHEMBL11263327 | 0.84 | TSHR (0.52) | HTR2CHTR2AHTR1AMAPTTSHR | |
| SCHEMBL10562985 | 0.81 | HTR2B (0.66) | NPSR1HTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL1667862 | 0.81 | NPSR1 (0.59) | NPSR1HTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL11269915 | 0.81 | MEN1 (0.68) | HTR2CHTR2AHTR2BALDH1A1MAPT | |
| SCHEMBL7292049 | 0.80 | NPSR1 (0.55) | NPSR1HTR2CHTR2AHTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL11193808 | 0.80 | HTR2B (0.64) | NPSR1HTR2CHTR2AHTR2BHTR1A | |
| SCHEMBL2008740 | 0.80 | TRPV1 (0.47) | NPSR1HTR2CHTR2AHTR2BHTR1A | |
| Water SCHEMBL10561845 | 0.80 | HTR2B (0.64) | NPSR1HTR2CHTR2AHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057631-B1 | ((INDOL-3-YL)-3-AMINO-2 PROPIONYLOXY)-2-ACETIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | PANMEDICA (FR) | 1985-02-20 | — | — | EP | claimed |
| EP-0522082-A4 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE | — | 1993-06-09 | — | — | EP | disclosed |
| EP-0522082-A1 | MULTI-FUNCTIONAL PHARMACEUTICAL COMPOUNDS AND METHODS OF USE. | GLASKY ALVIN J (US) | 1993-01-13 | — | — | EP | disclosed |