Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.37 |
| ▸ | PPARD | Q03181 | 7/20 | 0.37 |
| ▸ | PPARG | P37231 | 6/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035195 | 0.82 | PPARA (0.40) | PPARAPPARDPPARGTBXAS1 | |
| SCHEMBL1034265 | 0.81 | IDH1 (0.43) | PPARD | |
| SCHEMBL1030631 | 0.81 | PPARD (0.44) | PPARAPPARDPPARG | |
| SCHEMBL1032891 | 0.77 | BCL2L1 (0.37) | TBXAS1 | |
| SCHEMBL1030579 | 0.77 | FBP1 (0.38) | PPARAPPARDPPARG | |
| SCHEMBL27829362 | 0.76 | KCNK3 (0.41) | TBXAS1CNR2 | |
| SCHEMBL1035193 | 0.76 | PPARD (0.47) | PPARAPPARDPPARG | |
| SCHEMBL4655072 | 0.76 | LMNA (0.38) | PPARG | |
| SCHEMBL1082173 | 0.75 | PPARD (0.46) | PPARAPPARDPPARGTBXAS1 | |
| SCHEMBL1032853 | 0.75 | PPARA (0.40) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424917-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-2277874-B1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | NIPPON CHEMIPHAR CO (JP) | 2018-06-27 | — | — | EP | disclosed |
| EP-2277874-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2011-01-26 | — | — | EP | disclosed |