Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822593 | 0.87 | NPC1 (0.48) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL10483542 | 0.87 | ALDH1A1 (0.51) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL10483431 | 0.85 | NPC1 (0.51) | HSD17B10HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL10822388 | 0.84 | MAPT (0.53) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL10822753 | 0.84 | ABCC9 (0.47) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL9566406 | 0.81 | HDAC1 (0.53) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL9566451 | 0.81 | SMN1; SMN2 (0.56) | HDAC1HDAC3HDAC2NPC1RAB9A | |
| SCHEMBL11591466 | 0.81 | HDAC1 (0.60) | HSD17B10HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL11591085 | 0.81 | HDAC1 (0.60) | HSD17B10HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL8413034 | 0.80 | HDAC1 (0.56) | HDAC1HDAC3HDAC2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | claimed |
| US-4554275-A | Triazine derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 1985-11-19 | — | — | US | claimed |
| US-4593025-A | A 2-naphthyl-4,6-diamino-s-triazine compound | NIPPON SHINYAKU CO., LTD. (JP) | 1986-06-03 | — | — | US | disclosed |