Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | IDH1 | O75874 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823421 | 0.96 | MEN1 (0.48) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823435 | 0.88 | KMT2A (0.52) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823386 | 0.87 | TIMP3 (0.47) | MEN1KMT2AMAPTLMNATIMP3 | |
| SCHEMBL10823717 | 0.85 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823670 | 0.83 | KMT2A (0.52) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823442 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823696 | 0.83 | TIMP3 (0.47) | MEN1KMT2AMAPTLMNATIMP3 | |
| SCHEMBL10823596 | 0.82 | TRPV1 (0.51) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823434 | 0.82 | MEN1 (0.50) | MEN1KMT2AMAPTLMNAMAPK1 | |
| SCHEMBL10823589 | 0.81 | IDH1 (0.53) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |