Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823696 | 0.95 | TIMP3 (0.47) | TIMP3MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823404 | 0.87 | MEN1 (0.48) | TIMP3MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823707 | 0.85 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL10823589 | 0.84 | IDH1 (0.53) | — | |
| SCHEMBL10823421 | 0.83 | MEN1 (0.48) | TIMP3MEN1KMT2AMAPTLMNA | |
| SCHEMBL11347634 | 0.82 | TIMP3 (0.61) | TIMP3MEN1KMT2AMAPTPRMT1 | |
| SCHEMBL10823431 | 0.81 | CHEK1 (0.45) | TIMP3MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823352 | 0.81 | PTGES (0.41) | MEN1KMT2AGAAGFERALDH1A1 | |
| SCHEMBL10823667 | 0.80 | MEN1 (0.44) | TIMP3MEN1KMT2AMAPTLMNA | |
| SCHEMBL10823581 | 0.80 | IDH1 (0.53) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |