SCHEMBL10823447

SCHEMBL10823447

O=C(Nc1cccc(S(=O)(=O)Nc2cc(O)cc3cc(S(=O)(=O)O)ccc23)c1)Nc1cccc(S(=O)(=O)Nc2cc(O)cc3cc(S(=O)(=O)O)ccc23)c1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 2/20 0.54
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ LMNA P02545 2/20 0.48
▸ MAPT P10636 2/20 0.48
▸ MAPK1 P28482 2/20 0.48
▸ NPSR1 Q6W5P4 2/20 0.47
▸ ALOX12 P18054 1/20 0.47
▸ SIRT1 Q96EB6 1/20 0.46
▸ CASP6 P55212 1/20 0.46
▸ PKM P14618 1/20 0.45
▸ HTT P42858 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ ENPP2 Q13822 1/20 0.43
▸ CASR P41180 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10823769 0.91 PRMT1 (0.54) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823561 0.84 PRMT1 (0.51) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823345 0.84 PRMT1 (0.67) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823596 0.82 TRPV1 (0.51) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823506 0.82 PRMT1 (0.45) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL11342887 0.82 TIMP3 (0.55) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823504 0.82 PRMT1 (0.54) PRMT1SIRT1ENPP2
SCHEMBL10823380 0.81 MEN1 (0.49) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823416 0.81 MEN1 (0.49) PRMT1MEN1KMT2ALMNAMAPT
SCHEMBL10823723 0.81 PRMT1 (0.52) PRMT1MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-H83-H Dental antiplaque agents and inhibitors of connective tissue destruction AMERICAN CYANAMID COMPANY (US) 1986-07-01 — — US disclosed
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