Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823744 | 0.92 | PRMT1 (0.44) | PRMT1CASP6MEN1KMT2AGFER | |
| SCHEMBL10823437 | 0.85 | CASP6 (0.44) | PRMT1CASP6MEN1KMT2AGFER | |
| SCHEMBL10823539 | 0.84 | PRMT1 (0.57) | PRMT1CASP6MEN1KMT2AMAPT | |
| SCHEMBL10823757 | 0.83 | PRMT1 (0.62) | PRMT1CASP6MEN1KMT2AMAPT | |
| SCHEMBL11354729 | 0.83 | PRMT1 (0.44) | PRMT1CASP6MEN1KMT2ALMNA | |
| SCHEMBL10823472 | 0.83 | PTGES (0.46) | PRMT1CASP6MEN1KMT2AGFER | |
| SCHEMBL10823390 | 0.82 | HKDC1 (0.46) | PRMT1CASP6MEN1KMT2AENPP2 | |
| SCHEMBL10823447 | 0.82 | PRMT1 (0.54) | PRMT1CASP6MEN1KMT2ALMNA | |
| SCHEMBL10823779 | 0.82 | EP300 (0.49) | PRMT1MEN1KMT2AGFERPOLB | |
| SCHEMBL10823504 | 0.82 | PRMT1 (0.54) | PRMT1SIRT1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |