Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.50 |
| ▸ | NEK2 | P51955 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TIMP3 | P35625 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823703 | 0.91 | PRMT1 (0.55) | PRMT1CHEK1CDK8NEK2LIMK1 | |
| SCHEMBL10823438 | 0.88 | MEN1 (0.49) | PRMT1CHEK1CDK8NEK2LIMK1 | |
| SCHEMBL11351829 | 0.84 | TIMP3 (0.58) | PRMT1LMNATIMP3MEN1KMT2A | |
| SCHEMBL10823694 | 0.82 | PRMT1 (0.53) | PRMT1LMNATIMP3MEN1KMT2A | |
| SCHEMBL10823455 | 0.82 | PRMT1 (0.53) | PRMT1LMNATIMP3MEN1KMT2A | |
| SCHEMBL10823561 | 0.80 | PRMT1 (0.51) | PRMT1CHEK1CDK8NEK2LIMK1 | |
| SCHEMBL10823632 | 0.80 | PRMT1 (0.60) | PRMT1LMNATIMP3SIRT1 | |
| SCHEMBL10823413 | 0.80 | PRMT1 (0.53) | PRMT1LMNATIMP3KMT2ASIRT1 | |
| SCHEMBL10823698 | 0.79 | PRMT1 (0.55) | PRMT1LMNAMEN1KMT2AMAPT | |
| SCHEMBL10823431 | 0.78 | CHEK1 (0.45) | CHEK1CDK8NEK2LIMK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |