Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 2/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | NEK2 | P51955 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | CD40LG | P29965 | 1/20 | 0.46 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823591 | 0.91 | PRMT1 (0.50) | PRMT1CHEK1CDK8NEK2LIMK1 | |
| SCHEMBL10823561 | 0.89 | PRMT1 (0.51) | PRMT1ENPP2CHEK1CDK8NEK2 | |
| SCHEMBL10823604 | 0.86 | ENPP2 (0.53) | PRMT1ENPP2 | |
| SCHEMBL10823437 | 0.85 | CASP6 (0.44) | PRMT1ENPP2CHEK1CDK8NEK2 | |
| SCHEMBL11352189 | 0.84 | TIMP3 (0.57) | PRMT1ENPP2SIRT1NT5ECD40 | |
| SCHEMBL10823481 | 0.83 | PRMT1 (0.59) | PRMT1ENPP2SIRT1NT5ELMNA | |
| SCHEMBL10823431 | 0.82 | CHEK1 (0.45) | CHEK1CDK8NEK2LIMK1TIMP3 | |
| SCHEMBL10823413 | 0.81 | PRMT1 (0.53) | PRMT1SIRT1NT5ETIMP3LMNA | |
| SCHEMBL10823632 | 0.81 | PRMT1 (0.60) | PRMT1SIRT1NT5ETIMP3LMNA | |
| SCHEMBL10823694 | 0.81 | PRMT1 (0.53) | PRMT1SIRT1TIMP3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |