Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 5/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TYMP | P19971 | 2/20 | 0.42 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.40 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823650 | 0.81 | KMT2A (0.53) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL4950435 | 0.80 | KMT2A (0.50) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL31282172 | 0.78 | KMT2A (0.49) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL425895 | 0.77 | KMT2A (0.49) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL11239615 | 0.76 | CYP2C19 (0.69) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL12862593 | 0.76 | TYMP (0.60) | TYMPALDH1A1 | |
| SCHEMBL15314041 | 0.75 | CYP2C19 (0.47) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL1226226 | 0.75 | GRIA1 (0.60) | HTTKMT2ACYP1A2GRIA1GRIA2 | |
| SCHEMBL11238675 | 0.74 | CYP2C19 (0.79) | HTTKMT2ACYP2C9MAPTCYP1A2 | |
| SCHEMBL5983288 | 0.73 | KMT2A (0.44) | HTTKMT2ACYP2C9MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61010565-A | — | — | None | — | — | JP | disclosed |
| JP-S6110565-A | PREPARATION OF URACIL-5-CARBOXYLIC ACID ESTER | TAKEDA CHEM IND LTD | 1986-01-18 | — | — | JP | disclosed |