SCHEMBL425895

SCHEMBL425895

CNCn1cc(C(=O)O)c(=O)[nH]c1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
CYP2C9 P11712 2/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.46
CYP1A2 P05177 4/20 0.44
CYP2C19 P33261 3/20 0.44
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.40
HPGD P15428 2/20 0.39
DDO Q99489 1/20 0.39
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.36
GRIA1 P42261 3/20 0.36
GRIA2 P42262 3/20 0.36
GRIA4 P48058 3/20 0.36
GRIK5 Q16478 3/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9054601 0.84 KDM3B (0.39) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL5983288 0.82 KMT2A (0.44) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL10823650 0.81 KMT2A (0.53) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL31282172 0.78 KMT2A (0.49) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL10823643 0.77 HTT (0.56) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL11239615 0.76 CYP2C19 (0.69) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL17278321 0.75 LMNA (0.50) KMT2ACYP1A2SMN1; SMN2HPGDKDM4E
SCHEMBL6572744 0.75 GRIA1 (0.49) HPGDMAPK1GRIA1GRIA2GRIA4
SCHEMBL11238675 0.74 CYP2C19 (0.79) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL8672229 0.72 KMT2A (0.45) KMT2ACYP2C9MAPTHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 491 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146073-A1 T CELL RECEPTORS TARGETING MUTATED CDKN2A THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2026-05-28 US disclosed
US-12638452-B2 Nanopore assemblies and uses thereof OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-26 US disclosed
US-20250332186-A1 Methods and Compositions Relating to p62/SQSTM1 for the Treatment and Prevention of Inflammation-Associated Diseases CURELAB ONCOLOGY INC (US) 2025-10-30 US disclosed
US-20250263462-A1 ANTI-MUTATED KRAS T CELL RECEPTORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-08-21 US disclosed
US-20250018040-A1 ANTI-MESOTHELIN POLYPEPTIDES, PROTEINS, AND CHIMERIC ANTIGEN RECEPTORS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (US) 2025-01-16 US disclosed
CN-118949941-A Nanopore assembly and uses thereof 牛津纳米孔科技公开有限公司 2024-11-15 CN disclosed
US-20240299510-A1 ANTIBODY-GUIDED PCSK9-MIMICKING IMMUNOGENS LACKING 9-RESIDUE SEQUENCE OVERLAP WITH HUMAN PROTEINS THE UNITED STATES OF AMERICA,AS REPRESENTED BY THE SECRETARY,DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-09-12 US disclosed
US-20240265999-A1 METHODS AND SYSTEMS FOR METAGENOMICS ANALYSIS IDBYDNA INC. 2024-08-08 US disclosed
US-12054742-B2 Compositions and methods to derive mesodermal lineage cells and mixed tissue organoids from embryonic stem cells REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-08-06 US disclosed
US-20240229051-A9 CHLOROPLAST CYTOSINE BASE EDITORS AND MITOCHONDRIA CYTOSINE BASE EDITORS IN PLANTS NATIONAL SCIENCE FOUNDATION 2024-07-11 US disclosed
WO-2001042305-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001042304-A1 INTERLEUKIN-1 RECEPTOR ANTAGONIST-RELATED MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001042465-A2 CHORDIN-LIKE MOLECULES AND USES THEREOF AMGEN, INC. (US) 2001-06-14 WO disclosed
WO-2001011050-A1 Fhm, A NOVEL MEMBER OF THE TNF LIGAND SUPERGENE FAMILY AMGEN INC. (US) 2001-02-15 WO disclosed
WO-2001010908-A1 NTR3, A MEMBER OF THE TNF-RECEPTOR SUPERGENE FAMILY AMGEN INC. (US) 2001-02-15 WO disclosed
WO-2001007074-A1 VGF SELECTIVE BINDING AGENTS AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 WO disclosed
WO-2001007477-A1 VGF POLYPEPTIDES AND METHODS OF TREATING VGF-RELATED DISORDERS AMGEN, INC. (US) 2001-02-01 WO disclosed
EP-0476071-A4 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME 1992-11-04 EP disclosed
EP-0476071-A1 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME GILEAD SCIENCES, INC. (US) 1992-03-25 EP disclosed
WO-1990015065-A1 EXONUCLEASE-RESISTANT OLIGONUCLEOTIDES AND METHODS FOR PREPARING THE SAME GILEAD SCIENCES, INC. (US) 1990-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146073-A1 T CELL RECEPTORS TARGETING MUTATED CDKN2A TP53, CD74, HLA-C KMT2A 1370/4885CYP2C9 3468/4885MAPT 4121/4885
US-12638452-B2 Nanopore assemblies and uses thereof FAM83A, SCNN1G, SCN3A KMT2A 1925/4885CYP2C9 3699/4885MAPT 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.