SCHEMBL4950435

SCHEMBL4950435

O=C(O)c1cn(CO)c(=O)[nH]c1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
CYP2C9 P11712 2/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.46
CYP1A2 P05177 5/20 0.45
CYP2C19 P33261 3/20 0.45
GAA P10253 2/20 0.45
MEN1 O00255 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
DDO Q99489 1/20 0.42
GRIA1 P42261 4/20 0.40
GRIA2 P42262 4/20 0.40
GRIA4 P48058 4/20 0.40
GRIK5 Q16478 4/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 2/20 0.40
BLM P54132 1/20 0.40
GRIA3 P42263 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
KDM3B Q7LBC6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10823650 0.84 KMT2A (0.53) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL31282172 0.84 KMT2A (0.49) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL18640363 0.81 KMT2A (0.50) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL425895 0.80 KMT2A (0.49) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL10823643 0.80 HTT (0.56) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL11239615 0.78 CYP2C19 (0.69) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL11238675 0.76 CYP2C19 (0.79) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL5983288 0.75 KMT2A (0.44) KMT2ACYP2C9MAPTHTTCYP1A2
SCHEMBL827876 0.73 LMNA (0.58) KMT2AMAPTCYP1A2GRIA1GRIA2
SCHEMBL8672229 0.73 KMT2A (0.45) KMT2ACYP2C9MAPTHTTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106695-A1 TARGETED NANOPARTICLES ENCAPSULATING WATER-SOLUBLE THERAPEUTICS, METHODS OF PRODUCTION, AND USE OPTIMEOS LIFE SCIENCES, INC. (US) 2026-05-21 WO disclosed
WO-2026098357-A1 FREEZE-DRIED NUCLEIC ACID-LOADED LIPID NANOPARTICLE AND RECONSTITUTION METHOD THEREOF KUDO BIOTECHNOLOGY, INC. (US) 2026-05-15 WO disclosed
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS PFIZER INC. (US) 2026-05-14 US disclosed
WO-2026088119-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO disclosed
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION TRILINK BIOTECHNOLOGIES, LLC (US) 2026-04-23 US disclosed
EP-4728076-A1 METHOD FOR STABILIZING RNA Pfizer Inc. (US) 2026-04-22 EP disclosed
EP-4729614-A1 SYSTEM AND METHOD FOR SEPARATING MRNA Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-22 EP disclosed
EP-4720094-A1 MUTATED FRAGMENT OF VZV GLYCOPROTEIN E Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-08 EP disclosed
US-12594242-B2 Lipid compounds and lipid nanoparticle compositions Suzhou Abogen Biosciences Co., Ltd. (CN) 2026-04-07 US disclosed
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
WO-2017066791-A1 SUGAR SUBSTITUTED MRNA CAP ANALOGS MODERNATX, INC. (US) 2017-04-20 WO disclosed
WO-2017049286-A1 POLYNUCLEOTIDES CONTAINING A MORPHOLINO LINKER MODERNA THERAPEUTICS, INC. (US) 2017-03-23 WO disclosed
WO-2017049275-A2 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNA THERAPEUTICS, INC. (US) 2017-03-23 WO disclosed
WO-2017049245-A2 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX, INC. (US) 2017-03-23 WO disclosed
US-7329649-B2 Combinatorial methods for inducing cancer cell death THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2008-02-12 US disclosed
US-20070293453-A1 Combinatorial Methods For Inducing Cancer Cell Death NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-12-20 US disclosed
US-20040191223-A1 Combinatorial methods for inducing cancer cell death NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-09-30 US disclosed
EP-1425399-A2 COMBINATORIAL METHODS FOR INDUCING CANCER CELL DEATH The Trustees of Columbia University in the City of New York (US) 2004-06-09 EP disclosed
US-20030082140-A1 Combinatorial methods for inducing cancer cell death NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-05-01 US disclosed
WO-2003016499-A2 COMBINATORIAL METHODS FOR INDUCING CANCER CELL DEATH THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2003-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109977-A1 MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION RNGTT, RNMT, UPF1 KMT2A 1224/4885CYP2C9 4297/4885MAPT 1867/4885
US-20260130987-A1 VACCINATION AGAINST PNEUMOCCOCAL AND COVID-19 INFECTIONS SARS1, CD14, PYCARD KMT2A 4478/4885CYP2C9 1589/4885MAPT 929/4885
US-12594242-B2 Lipid compounds and lipid nanoparticle compositions NPC1, NPC1L1, PLIN3 KMT2A 2276/4885CYP2C9 862/4885MAPT 3750/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP KMT2A 4212/4885CYP2C9 4775/4885MAPT 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.