Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 2/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823704 | 0.88 | CA2 (0.52) | PTPN5CA2CA1HSD17B1HSD17B2 | |
| SCHEMBL11346743 | 0.83 | CASP6 (0.59) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL1413066 | 0.83 | NT5E (0.57) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL10823372 | 0.83 | NT5E (0.66) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL8100276 | 0.83 | NSD2 (0.71) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL10823488 | 0.82 | PRMT1 (0.64) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL11208714 | 0.82 | CASP6 (0.60) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL27676540 | 0.80 | NT5E (0.57) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL10711430 | 0.80 | NSD2 (0.57) | NT5EPTPN5NSD2DUSP3CASP7 | |
| SCHEMBL8440189 | 0.77 | NT5E (0.70) | NT5EPTPN5NSD2DUSP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |