SCHEMBL10823722

SCHEMBL10823722

C=CCN(C(=O)O)c1cccc2c1OC(C)(C)C2

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.43
PKM P14618 2/20 0.43
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11109613 0.86 LMNA (0.46) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL11111221 0.84 TSHR (0.34) LMNAPKMMAPTALDH1A1KDM4E
SCHEMBL946263 0.79 LMNA (0.49) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL10846575 0.78 LMNA (0.43) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL984570 0.76 POLB (0.39) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL11211592 0.75 LMNA (0.46) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL11138684 0.73 NPC1 (0.43) LMNAPOLBMAPTALDH1A1NPC1
SCHEMBL10483147 0.73 LMNA (0.39) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL11134996 0.72 LMNA (0.38) LMNAPKMPOLBMAPTALDH1A1
SCHEMBL11143267 0.72 LMNA (0.42) LMNAPOLBMAPTALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61134385-A None JP disclosed
JP-S61134385-A PRODUCTION OF BENZOFURANYLCARBAMATE MITSUBISHI CHEM IND LTD 1986-06-21 JP disclosed