SCHEMBL946263

SCHEMBL946263

CN(C(=O)O)c1cccc2c1OC(C)(C)C2

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.49
MAPT P10636 2/20 0.46
POLB P06746 2/20 0.46
PKM P14618 2/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ALDH1A1 P00352 3/20 0.43
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11211592 0.82 LMNA (0.46) LMNAMAPTPOLBPKMNPSR1
SCHEMBL11109613 0.82 LMNA (0.46) LMNAMAPTPOLBPKMNPSR1
SCHEMBL20307149 0.81 LMNA (0.46) LMNAMAPTPOLBPKMNPSR1
SCHEMBL10801507 0.80 GAA (0.33) LMNAMAPTPOLBKMT2A
SCHEMBL10823722 0.79 LMNA (0.43) LMNAMAPTPOLBPKMNPSR1
SCHEMBL10803618 0.76 RXRA (0.32) MAPTPOLB
SCHEMBL11171242 0.76 LMNA (0.46) LMNAMAPTPOLBPKMNPSR1
SCHEMBL10846575 0.76 LMNA (0.43) LMNAMAPTPOLBPKMNPSR1
SCHEMBL783714 0.75 LMNA (0.59) LMNAMAPTPOLBPKMNPSR1
SCHEMBL11039174 0.74 LMNA (0.44) LMNAMAPTPOLBPKMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116234786-A N-heterocyclic compounds as nitrification inhibitors 欧洲化学安特卫普公司 2023-06-06 CN claimed
US-20180007898-A1 BIOPESTICIDE COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-01-11 US claimed
WO-2001013719-A2 CONTAINER FOR PESTICIDES AVENTIS CROPSCIENCE S.A. (FR) 2001-03-01 WO claimed
EP-0300691-B1 PLANT-PROTECTIVE COMPOSITION CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1992-03-04 EP claimed
EP-0192118-B1 COMBINATION CARRIER GRANULES BAYER AG (DE) 1991-07-03 EP claimed
US-4943307-A WATER-INSOLUBLE MATERIALS IN SOLVENT MIXTURE CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1990-07-24 US claimed
EP-0203954-B1 BENZOFURAN DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1989-09-06 EP claimed
EP-0110564-B1 NEMATOCIDAL AND INSECTICIDAL COMPOSITION AND METHOD FOR THE CONTROL OF THE SAID PESTS CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1987-01-07 EP claimed
EP-0192118-A2 Combination carrier granules BAYER AG (DE) 1986-08-27 EP claimed
EP-0064379-B1 PESTICIDAL COMPOSITION AND METHODS FOR CONTROLLING PESTS UNIROYAL, INC. (US) 1985-08-14 EP claimed
US-4315017-A Triazole derivatives BASF AKTIENGESELLSCHAFT (DE) 1982-02-09 US claimed
US-4086246-A REACTION OF PHOSGENE WITH A PHENOL AND PRIMARY AMINE CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA (HU) 1978-04-25 US claimed
CN-118647376-A Compositions comprising a beta blocker and a cholinesterase inhibitor for the treatment of neurodegenerative diseases 诺亚博士生物科技有限公司 2024-09-13 CN disclosed
CN-116829146-A Complex pharmaceutical composition for treating brain diseases comprising cholinesterase inhibitor and antioxidant 诺亚博士生物科技有限公司 2023-09-29 CN disclosed
US-20210352892-A1 MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT UNIVERSITY OF UTAH RESEARCH FOUNDATION 2021-11-18 US disclosed
WO-2020210750-A1 MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2020-10-15 WO disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932632-A Insecticidal compositions containing an organophosphorus compound and a thiolcarbamate BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180007898-A1 BIOPESTICIDE COMPOSITIONS AND METHODS FOR THEIR PREPARATION AND USE DDT, LCT, BPHL LMNA 862/4885MAPT 1824/4885POLB 1684/4885
US-20210352892-A1 MACROMOLECULAR AND NONPARTICULATE AGROCHEMICALS TO REDUCE VAPOR DRIFT ACP1, PTMS, VDAC1 LMNA 3816/4885MAPT 806/4885POLB 1662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.