Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.50 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823726 | 0.92 | PSD (0.49) | HKDC1PSDEP300KAT2BKAT8 | |
| SCHEMBL10823562 | 0.88 | MEN1 (0.49) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL10823651 | 0.87 | MEN1 (0.46) | HKDC1PSDEP300KAT2BKAT8 | |
| SCHEMBL10823362 | 0.87 | MEN1 (0.46) | HKDC1PSDEP300KAT2BKAT8 | |
| SCHEMBL10823412 | 0.87 | AURKB (0.47) | HKDC1PSDEP300KAT2BKAT8 | |
| SCHEMBL10823487 | 0.84 | EP300 (0.46) | HKDC1PSDEP300KAT2BKAT8 | |
| SCHEMBL10823442 | 0.84 | MEN1 (0.49) | KMT2AMEN1LMNAHTTALDH1A1 | |
| SCHEMBL10823431 | 0.83 | CHEK1 (0.45) | HKDC1PSDEP300KAT2BKAT8 | |
| SCHEMBL10823346 | 0.83 | CHEK1 (0.45) | KMT2AMEN1LMNAHTTMAPT | |
| SCHEMBL11342760 | 0.82 | TIMP3 (0.56) | KMT2AMEN1ALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H83-H | Dental antiplaque agents and inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1986-07-01 | — | — | US | disclosed |