SCHEMBL10823968

SCHEMBL10823968

[c]1sccc1-c1ncccc1-c1cccs1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
CYP2E1 P05181 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2A6 P11509 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2B6 P20813 1/20 0.37
TDO2 P48775 2/20 0.36
ALDH1A1 P00352 4/20 0.36
TSHR P16473 1/20 0.36
GLO1 Q04760 1/20 0.35
CYP19A1 P11511 1/20 0.35
CDK5 Q00535 2/20 0.34
LTK P29376 1/20 0.34
MST1R Q04912 1/20 0.34
DYRK1A Q13627 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
CDK5R1 Q15078 1/20 0.34
PDE3B Q13370 1/20 0.34
PDE3A Q14432 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29675365 0.80 CYP11B1 (0.48) CYP11B1CYP11B2CYP2E1CYP3A4CYP2A6
SCHEMBL4170768 0.80 CYP11B1 (0.48) CYP11B1CYP11B2CYP2E1CYP3A4CYP2A6
SCHEMBL30497068 0.79 CYP11B1 (0.47) CYP11B1CYP11B2CYP2E1CYP3A4CYP2A6
SCHEMBL117020 0.74 CYP3A4 (0.41) CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6
SCHEMBL31500784 0.73 SMN1; SMN2 (0.50) CYP11B1CYP11B2CYP2E1CYP3A4CYP2A6
SCHEMBL27331118 0.70 ALDH1A1 (0.50) ALDH1A1TSHRCYP19A1CDK5CDK5R1
SCHEMBL28609066 0.70 CYP11B1 (0.40) CYP11B1CYP11B2CYP2E1CYP3A4CYP2A6
SCHEMBL14380313 0.69 CYP2E1 (0.42) CYP11B1CYP11B2CYP2E1CYP3A4CYP2A6
Acetic Acid SCHEMBL28652614 0.69 TOP2A (0.44) CYP11B1CYP11B2ALDH1A1TSHRGLO1
SCHEMBL27896364 0.68 GLO1 (0.47) CYP2E1CYP3A4CYP2A6CYP2C9CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61037705-A None JP disclosed
JP-S6137705-A AGRICULTURAL AND HORTICULTURAL GERMICIDE CONTAINING HETEROALLENE OLIGOMER DERIVATIVE HOKKO CHEM IND CO LTD 1986-02-22 JP disclosed