SCHEMBL10824464

SCHEMBL10824464

C/C(=C\C(=O)O)C(C)(C)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
NR4A1 P22736 1/20 0.32
NR4A2 P43354 1/20 0.32
NR4A3 Q92570 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
RARA P10276 1/20 0.30
RARB P10826 1/20 0.30
RARG P13631 1/20 0.30
RXRA P19793 1/20 0.30
RXRB P28702 1/20 0.30
RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10824467 1.00 ALDH1A1 (0.45) ALDH1A1TSHRKDM4EATMNR4A1
SCHEMBL5507898 0.80 KDM4E (0.34) ALDH1A1TSHRKDM4EATMNR4A1
SCHEMBL5507895 0.80 KDM4E (0.34) ALDH1A1TSHRKDM4EATMNR4A1
SCHEMBL1783630 0.80 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL1783632 0.80 ALDH1A1 (0.40) ALDH1A1TSHR
SCHEMBL16376833 0.77 ALDH1A1 (0.33) ALDH1A1TSHRKDM4EATM
SCHEMBL936907 0.72 NR4A1 (0.41) KDM4EATMNR4A1NR4A2NR4A3
SCHEMBL3454104 0.72 NR4A1 (0.41) KDM4EATMNR4A1NR4A2NR4A3
SCHEMBL936905 0.72 NR4A1 (0.41) KDM4EATMNR4A1NR4A2NR4A3
SCHEMBL10669206 0.72 RIPK1 (0.36) TSHRKDM4EATMRXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61065895-A None JP disclosed
JP-61197590-A None JP disclosed
JP-S61197590-A QUASSINOID COMPOUND AND PRODUCTION THEREOF SUNTORY LTD 1986-09-01 JP disclosed
JP-S6165895-A NOVEL QUASSINOID COMPOUND AND ITS PRODUCTION SUNTORY LTD 1986-04-04 JP disclosed