Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824926 | 0.81 | KMT2A (0.42) | ALDH1A1TDP1HPGDKDM4EGAA | |
| SCHEMBL9046798 | 0.80 | HTR2A (0.43) | ALDH1A1TDP1HSD17B10HPGDKDM4E | |
| SCHEMBL10921909 | 0.78 | TBXA2R (0.53) | TBXA2RTBXAS1 | |
| SCHEMBL9377375 | 0.77 | TBXA2R (0.45) | ALDH1A1HSD17B10HPGDKDM4EGAA | |
| SCHEMBL10564573 | 0.74 | HPGD (0.42) | ALDH1A1HPGDGAAMAPTNPC1 | |
| SCHEMBL7972519 | 0.72 | MAOA (0.40) | ALDH1A1TDP1HSD17B10HPGDKDM4E | |
| SCHEMBL9047807 | 0.71 | HTR2A (0.38) | ALDH1A1TDP1HSD17B10HPGDKDM4E | |
| SCHEMBL13614283 | 0.69 | ALDH1A1 (0.49) | ALDH1A1TDP1HSD17B10HPGDKDM4E | |
| SCHEMBL8126444 | 0.69 | KDM4E (0.44) | ALDH1A1HSD17B10HPGDKDM4EGAA | |
| SCHEMBL8797201 | 0.69 | KMT2A (0.39) | GAAMAPTTBXA2RTSHRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61152674-A | — | — | None | — | — | JP | disclosed |
| JP-S61152674-A | PRODUCTION OF DIBENZO(B,E)OXEPINE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1986-07-11 | — | — | JP | disclosed |