Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643912 | 0.76 | ALDH1A1 (0.44) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL2093826 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL6542108 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL11610235 | 0.71 | LMNA (0.49) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL22879338 | 0.69 | ALDH1A1 (0.39) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL10825668 | 0.69 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNATRPM8HPGD | |
| O-Xylene SCHEMBL10797227 | 0.67 | TSHR (0.56) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL516435 | 0.66 | TSHR (0.53) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL29521738 | 0.66 | TSHR (0.53) | ALDH1A1TSHRLMNACYP3A4ACHE | |
| SCHEMBL23641843 | 0.66 | MAPT (0.46) | ALDH1A1TSHRLMNACYP3A4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595781-A | N,N'-dithiobisformanilides and their use in diene rubber | MONSANTO COMPANY (US) | 1986-06-17 | — | — | US | disclosed |
| US-4391953-A | Diene rubber compositions containing N,N'-dithioformanilide crosslinkers | MONSANTO COMPANY (US) | 1983-07-05 | — | — | US | disclosed |