Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.54 |
| ▸ | APP | P05067 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PLEC | Q15149 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10826169 | 1.00 | LMNA (0.58) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL10826286 | 0.86 | LMNA (0.57) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL10826288 | 0.86 | LMNA (0.57) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL11335643 | 0.83 | LMNA (0.52) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL3672656 | 0.80 | LMNA (0.60) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL3681804 | 0.80 | LMNA (0.60) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL8887928 | 0.80 | PPARA (0.60) | KDM4EKMT2A | |
| SCHEMBL8887936 | 0.80 | PPARA (0.60) | KDM4EKMT2A | |
| SCHEMBL11179981 | 0.79 | KDM4E (0.74) | LMNAKDM4EAKR1C3APPALDH1A1 | |
| SCHEMBL5848040 | 0.79 | KDM4E (0.87) | LMNAKDM4EAKR1C3APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618627-A | ALLERGIES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-21 | — | — | US | disclosed |
| EP-0125919-A2 | Catechol derivatives, their production and intermediates therefor, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1984-11-21 | — | — | EP | disclosed |